Combine chili powder, Italian seasoning, cumin, salt and pepper in small bowl. Set aside.
Heat oil in large skillet over medium heat. Add mushrooms and cook 5 minutes, or until brown. Add turkey and cook 5-7 minutes, or until cooked thoroughly. Add seasoning and 3 Tbsp. water pan. Cook 2-3 minutes.
Top tortillas with turkey and with your favorite taco toppings.